Transcription Factors

Some articles on transcription factor, transcription factors, factor, transcriptions:

Cis-regulatory Module - Identification and Computational Prediction of CRMs
... Most algorithms try to search for significant combinations of transcription factor binding sites (DNA binding sites) in promoter sequences of co-expressed genes ... in gene expression datasets between transcription factors and target genes ... modules include Stubb uses hidden Markov models to identify statistically significant clusters of transcription factor combinations ...
Ch IP-sequencing - Uses of ChIP-seq
... ChIP-seq is used primarily to determine how transcription factors and other chromatin-associated proteins influence phenotype-affecting mechanisms ... Specific DNA sites in direct physical interaction with transcription factors and other proteins can be isolated by chromatin immunoprecipitation ... This can be applied to the set of ChIP-able proteins and modifications, such as transcription factors, polymerases and transcriptional machinery, structural proteins, protein ...
Dentatorubral-pallidoluysian Atrophy - Pathology - Neuronal Intranuclear Inclusions
... NIIs are immunopositive for several transcription factors such as TATA binding protein (TBP), TBP-associated factor (TAFII130), Sp1, camp-responsive element-binding protein (CREB) and CREB-binding protein (CBP) ... It has been proposed that recruitment of transcription factors into NIIs may induce transcriptional abnormalities that contribute to progressive neuronal degeneration ... and 7), have been demonstrated to sequester some of the same transcriptions factors ...
Cis-regulatory Module
... usually 100-1000 DNA base pairs in length, where a number of transcription factors can bind and regulate expression of nearby genes ... Regulatory elements are binding sites for transcription factors, which are involved in gene regulation ... modules are non-random clusters at their specified target site that contain transcription factor binding sites ...
SOX6
... Gene Gene Ontology Molecular function • DNA binding • sequence-specific DNA binding transcription factor activity • protein binding • sequence-specific DNA binding ... The SOX gene family encodes a group of transcription factors defined by the conserved high mobility group (HMG) DNA-binding domain ... Unlike most transcription factors, SOX transcription factors bind to the minor groove of DNA, causing a 70- to 85-degree bend and introducing local conformational changes ...

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