Type II Topoisomerase
Type II topoisomerases cut both strands of the DNA helix simultaneously in order to manage DNA tangles and supercoils. They use the hydrolysis of ATP, unlike Type I topoisomerase. In this process, these enzymes change the linking number of circular DNA by ±2.
Read more about Type II Topoisomerase: Function, Topology Simplification, Classification, Structure of Type IIA Topoisomerases, Structures of Type IIB Topoisomerases, Strand Passage Mechanism of Type II Topoisomerases, DNA Cleavage Mechanism of Type IIA Topoisomerases, Catenation, Inhibition
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