Cohesin

Cohesin is a protein complex that regulates the separation of sister chromatids during cell division, either mitosis or meiosis.

Read more about Cohesin:  Structure, Function, Dissociation of Sister Chromatid Cohesion, Mechanism of Action, Localization of Cohesin Rings, Evolution, Clinical Significance

Other articles related to "cohesin":

Dockerin
... The dockerin's binding partner is the cohesin domain, located on the scaffoldin protein ... dockerin domains of the enzyme constituents of the cellulosome and the cohesin domains of the scaffoldin protein is essential to the construction of the cellulosome complex ... in solution, as well as in complex with Cohesin ...
Cohesin - Clinical Significance
... The term "cohesinopathy" has been used to describe conditions affecting the cohesin complex. ...
Spindle Checkpoint - Sister Chromatids Cohesion During Mitosis - Function of Cohesion and Its Dissolution
... Indeed, a decrease in the cellular levels of cohesin generates the premature separation of sister chromatids, as well as defects in chromosome congression at the metaphase plate and delocalization of the ... The proposed structure for the cohesin complex suggests that this complex connects directly both sister chromatids ... In this proposed structure, the SMC components of cohesin play a structural role, so that the SMC heterodimer may function as a DNA binding protein, whose conformation is regulated by ATP ...
CDC20 - Interactions
... Securin is a protein that inhibits separase, which in turn inhibits cohesin, a protein that holds sister chromatids together ... Therefore, in order for anaphase to progress, securin must be inhibited so that cohesin can be cleaved by separase ... both the degradation of Cdks and the cleavage of cohesin ...
SMC Protein - Species Distribution - Eukaryotic
... of SMC1 and SMC3 constitutes the core subunits of the cohesin complexes involved in sister chromatid cohesion ... melanogaster vertebrates SMC1α cohesin Smc1 Psm1 SMC-1 DmSmc1 SMC1α SMC1β cohesin (meiotic) - - - - SMC1β SMC2 condensin Smc2 Cut14 MIX-1 DmSmc2 CAP-E SMC3 cohesin Smc3 Psm3 SMC-3 DmSmc3 SMC3 SMC4 condensin Smc4 ...