Cohesin structure and function has been conserved in evolution. The SMC proteins are found in prokaryotes and have been conserved through evolution. The coiled coils of SMC1 and SMC3 are conserved with an amino acid divergence of less than 0.5%.
|Name||Saccharomyces cerevisiae||Schizosaccharomyces pombe||Drosophila||Vertebrates|
|Scc3||Scc3||Psc3||DmSA||SA1 and SA2|
Read more about this topic: Cohesin
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