TATA Box

The TATA box (also called Goldberg-Hogness box) is a DNA sequence (cis-regulatory element) found in the promoter region of genes in archaea and eukaryotes; approximately 24% of human genes contain a TATA box within the core promoter.

Considered to be the core promoter sequence, it is the binding site of either general transcription factors or histones (the binding of a transcription factor blocks the binding of a histone and vice versa) and is involved in the process of transcription by RNA polymerase.

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Other articles related to "tata, tata box":

RNA Polymerase II Holoenzyme - Preinitiation Complex - Assembly of The PIC
... The TATA-binding protein (TBP, a subunit of TFIID), TBPL1, or TBPL2 can bind the promoter or TATA box ... Most genes lack a TATA box and use an initiator element (Inr) or downstream core promoter instead ... TAFs from TFIID can also be involved when the TATA box is absent ...
TATA Box - Overview
... The TATA box has the core DNA sequence 5'-TATAAA-3' or a variant, which is usually followed by three or more adenine bases ... It is normally bound by the TATA binding protein (TBP) in the process of transcription, which unwinds the DNA, and bends it through 80° ... The TATA box is usually found at the binding site of RNA polymerase II ...
Silencer (DNA) - In Prokaryotes and Eukaryotes - Eukaryotes - Repression of The TATA Box
... A common basal promoter is the TATAAAAAA sequence known as the TATA box ... The TATA box is a complex with several different proteins including transcription factor II D (TFIID) which includes the TATA-binding protein (TBP) that binds to the TATA box along ... The TATA box also includes the transcription factor II B (TFIIB) which binds to both DNA and RNA polymerases ...

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