OCW may refer to:
- OpenCourseWare, university material that is available for all to see and use
- OCW, The Dutch Ministry of Education, Culture and Science
- OCW for Optimal Charge Weight, a system of developing handloads for rifles by Dan Newberry
- OCW, abbreviation of The Oxford Companion to Wine
- OCW, abbreviation of Oklahoma College for Women
- OneClick Wi-Fi, a Nintendo Wi-Fi Connection community website
- One cool word, a Vancouver-based arts magazine
- Ontario Championship Wrestling, a Canadian professional wrestling promotion