Nagle is a surname, and may refer to:
- Browning Nagle (born 1968), American football quarterback
- Chet Nagle (Chester A.?) (born 1936), American intelligence officer and author
- Courtney Nagle (born 1982) is an American professional tennis player.
- David R. Nagle (born 1943), Representative in the United States House of Representatives
- Don Nagle, American karate Grand Master
- Jack Nagle (1917-1991), head coach of the Marquette University men’s basketball team
- Jacob Nagle (1761-1841), Royal Navy sailor
- Jim Nagle (born 1977), American professional ice hockey player
- John Nagle, author of RFC896, see: Nagle's algorithm
- Kel Nagle (born 1920), Australian golfer
- Mackey Nagle, a recurring character on Smart Guy
- Margaret Nagle (born 1969), screenwriter and TV producer
- Matt Nagle (circa 1979-2007), one of the first people to use a brain-computer interface to restore functionality lost due to paralysis
- Nano Nagle (1718-1784), founder of the Presentation Sisters
- Noel Nagle (21st century), Irish musician
- Ron Nagle (born 1939), American ceramic sculptor
- William Nagle (author) (1947-2002), Australian soldier and author
- William Nagle (football coach) (19th century), former head coach of the Boston College college football program
See also Nagl
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