Methylenetetrahydrofolate Reductase - Regulation

Regulation

MTHFR activity may be inhibited by binding of dihydrofolate (DHF) and S-adenosylmethionine (SAM, or AdoMet). MTHFR can also be phosphorylated - this decreases its activity by ~20% and allows it to be more easily inhibited by SAM.

Read more about this topic:  Methylenetetrahydrofolate Reductase

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Famous quotes containing the word regulation:

    Nothing can be more real, or concern us more, than our own sentiments of pleasure and uneasiness; and if these be favourable to virtue and unfavourable to vice, no more can be requisite to the regulation of our conduct and behavior.
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