Methylenetetrahydrofolate Reductase

Methylenetetrahydrofolate reductase (MTHFR) is an enzyme that in humans is encoded by the MTHFR gene. Methylenetetrahydrofolate reductase catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a cosubstrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.

Read more about Methylenetetrahydrofolate ReductaseBiochemistry, Structure, Regulation, Interactive Pathway Map, Genetics, Reaction Schematic and Folate Pathway, As A Drug Target

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Methylenetetrahydrofolate Reductase (ferredoxin)
... In enzymology, a methylenetetrahydrofolate reductase (ferredoxin) (EC 1.5.7.1) is an enzyme that catalyzes the chemical reaction 5-methyltetrahydrofolate + 2 oxidized ... This enzyme is also called 5,10-methylenetetrahydrofolate reductase ...