Transcriptase

  • (noun): A polymerase associated with the process of transcription.

Some articles on transcriptase:

Lamivudine - Mechanism of Action
... It can inhibit both types (1 and 2) of HIV reverse transcriptase and also the reverse transcriptase of hepatitis B ... They inhibit the HIV reverse transcriptase enzyme competitively and act as a chain terminator of DNA synthesis ...
Reverse-transcriptase Inhibitor
... Reverse-transcriptase inhibitors (RTIs) are a class of antiretroviral drug used to treat HIV infection, tumors, and cancer ... RTIs inhibit activity of reverse transcriptase, a viral DNA polymerase enzyme that retroviruses need to reproduce ...
Reverse Transcriptase - Applications - Antiviral Drugs
... For more details on this topic, see Reverse transcriptase inhibitor ... As HIV uses reverse transcriptase to copy its genetic material and generate new viruses (part of a retrovirus proliferation circle), specific drugs have been designed to disrupt the ... Collectively, these drugs are known as reverse transcriptase inhibitors and include the nucleoside and nucleotide analogues zidovudine (trade name Retrovir), lamivudine (Epivir) and tenofovir (Vire ...
Reverse-transcriptase Inhibitor - Mechanisms of Resistance To Reverse Transcriptase Inhibitors
... with selective pressure from the drug leads to mutations in reverse transcriptase that make the virus less susceptible to NRTIs and NNRTIs ... Aspartate residues 110, 185, and 186 in the reverse transcriptase polymerase domain are important in the binding and incorporation of nucleotides ...
Emtricitabine/tenofovir/efavirenz - Mechanism of Action
... Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRT) of HIV-1 ... Emtricitabine is a nucleoside reverse transcriptase inhibitor (NRTI) of HIV-1.Tenofovir is a nucleotide reverse transcriptase inhibitor of HIV-1, but it can be classified as a NRTI ...