TFL may refer to:
- Tasmanian Football League, an Australian rules football competition
- Tensor fasciae latae muscle, a thigh/hip muscle
- "TfL", Transport for London, a public transport organisation in the London area
- The Flaming Lips, an American rock band
- Two Fat Ladies, a British cooking programme and colloquially the number 88 in bingo
- Tyskarna från Lund, a Swedish band
- The Fallen Lords, the first in the Myth series of video games
- TFL, Trainload Freight, British Rail freight division
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