Sodium Channel

Sodium Channel

Sodium channels are integral membrane proteins that form ion channels, conducting sodium ions (Na+) through a cell's plasma membrane. They are classified according to the trigger that opens the channel for such ions, i.e. either a voltage-change ("Voltage gated", "voltage sensitive" or "voltage dependant" sodium channel also called "VGSCs" or "Nav channel") or binding of a substance (a ligand) to the channel (ligand-gated sodium channels).

In excitable cells such as neurons, myocytes, and certain types of glia, sodium channels are responsible for the rising phase of action potentials.

Read more about Sodium Channel:  Ligand-gated, Role in Action Potential

Other articles related to "sodium, sodium channel, channels, sodium channels":

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... Sodium channel blockers are also used as local anesthetics and epilepsy treatments ... Sodium channel blockers have been proposed for use in the treatment of cystic fibrosis, but current evidence is mixed ... effect of some antidepressants is due to sodium channel blockade ...
Sodium Channel - Pharmacologic Modulation - Gating Modifiers
... The following toxins modify the gating of sodium channels Peptide based toxins μ-conotoxin δ-atracotoxin Scorpion venom toxins, such as Birtoxin ...

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