Organotellurium Chemistry - Applications - Organic Synthesis

Organic Synthesis

Diphenyl ditelluride is used as a source of PhTe- in organic synthesis. Some of its reactions are:

  • Organic reduction of aldehydes, alkenes, alkynes, nitro compounds, oxiranes to alkenes
  • Debromination of vicinal dibromides with E2 elimination

Other methods in organotellurium chemistry include:

  • Tellurium in vinylic tellurium trichlorides can be replaced by halides with a variety of reagents (iodine, NBS)
  • Detellurative cross-coupling reaction: Compounds of the type Ar2TeCl2 engage in a coupling reaction to the corresponding biaryls with Raney nickel or palladium
Another type is this Stille reaction:
  • Hydrotelluration: Compounds of the type RTeH react with alkynes R'CCH to R'HCCTeR with anti addition to a Z-alkene. In contrast hydrostannylation, hydrozirconation and hydroalumination in similar reactions react with syn addition.
  • Te/Li exchange in transmetallation is used in the synthesis of lithium reagents with demanding functional groups.
  • Allylic oxidation: like the selenium counterpart selenoxide oxidation, allylic telluroxides undergo -sigmatropic rearrangements forming allylic alcohols after hydrolysis.
  • Olefin synthesis: Like the selenium counterpart selenoxide elimination, certain telluroxides (RTeOR) can form alkenes on heating.

Read more about this topic:  Organotellurium Chemistry, Applications

Other articles related to "organic synthesis, synthesis, organic":

Synthetic Compound - Organic Synthesis
... Organic synthesis is a special branch of chemical synthesis dealing with the synthesis of organic compounds ... In the total synthesis of a complex product it may take multiple steps to synthesize the product of interest, and inordinate amounts of time ... Skill in organic synthesis is prized among chemists and the synthesis of exceptionally valuable or difficult compounds has won chemists such as Robert Burns Woodward the Nobel Prize for Chemistry ...
Organic Synthesis - Synthesis Design
... James Corey brought a more formal approach to synthesis design, based on retrosynthetic analysis, for which he won the Nobel Prize for Chemistry in 1990 ... Computer programs have been written for designing a synthesis based on sequences of generic "half-reactions" ...
List Of Nobel Laureates In Chemistry - Laureates
1905 Johann Friedrich Wilhelm Adolf von Baeyer Germany " the advancement of organic chemistry and the chemical industry, through his work on organic dyes and hydroaromatic compounds ... Prelog Yugoslavia/Switzerland "for his research into the stereochemistry of organic molecules and reactions" 1976 William N ... compounds, respectively, into important reagents in organic synthesis" Georg Wittig Federal Republic of Germany 1980 Paul Berg United States "for his fundamental ...
Charles Loring Jackson - The European Connection
... of Jackson's studies in Europe to the development of the organic chemistry industry in the United States should not be underestimated ... In the 1870s when Jackson traveled to Europe there literally was no organic synthesis being done in the United States either in academia or in industry ... very evident with the advent of World War I and World War II when the supply of strategic organic materials from Germany to the United States was cut off ...
Nuclear Chemistry - Spinout Areas - Uses Within Geology, Biology and Forensic Science - Biology
... By organic synthesis it is possible to create a complex molecule with a radioactive label that can be confined to a small area of the molecule ... By rapid organic synthesis, the 11C compound formed in the cyclotron is converted into the imaging agent which is then used for PET ... be made (as above), and it is possible to convert the target material into simple inorganic and organic compounds ...

Famous quotes containing the words synthesis and/or organic:

    The spider-mind acquires a faculty of memory, and, with it, a singular skill of analysis and synthesis, taking apart and putting together in different relations the meshes of its trap. Man had in the beginning no power of analysis or synthesis approaching that of the spider, or even of the honey-bee; but he had acute sensibility to the higher forces.
    Henry Brooks Adams (1838–1918)

    The following general definition of an animal: a system of different organic molecules that have combined with one another, under the impulsion of a sensation similar to an obtuse and muffled sense of touch given to them by the creator of matter as a whole, until each one of them has found the most suitable position for its shape and comfort.
    Denis Diderot (1713–1784)