NSE may refer to:
- education
- Norwegian School of Economics
- stock exchanges
- Nagoya Stock Exchange in Japan, Japan
- Nairobi Stock Exchange in Kenya, Kenya
- Nigerian Stock Exchange in Lagos, Nigeria Nigeria
- National Stock Exchange of India, India
- National Stock Exchange, the former name of Vilnius Stock Exchange, Lithuania
- companies and organizations
- National Society for Epilepsy, a United Kingdom-based epilepsy charity
- National Student Exchange, an exchange program for American and Canadian undergraduate students
- Network SouthEast, a former sector of British Rail
- National Support Element, a military term for a supply and support unit deployed primarily in Hungary as part of IFOR
- other uses
- Enolase 2, A.K.A. Neuron-Specific Enolase
- Namespace Shell Extension, discussed in Shell_extension
- Network Search Engine (also known as Network Search Element), a device that helps computer network routers accelerate one of the most common functions: searching for patterns/addresses in data packets
- NSE: Net Sphere Engineer, a manga by Tsutomu Nihei.
- National Spanish Examinations, an online assessment for students studying Spanish as a second language in the United States
- North-South Expressway, Malaysia
- North–South Expressway, Singapore
- Nu Skin Enterprises, a direct selling multi-level marketing company
- Neuron-specific enolase, Enolase 2
- Non-Speaking Extra, an Extra (actor)
- Navier-Stokes equations to describe motion of fluid substances
- Nmap Scripting Engine, a feature of the Nmap security scanner that allows users to write (and share) simple scripts that are executed in parallel, using the Lua programming language, to automate a wide variety of networking tasks.
- Nanoscale Science and Engineering
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