Lambe is a surname, and may refer to:
- Charles Lambe (1900-1960), Royal Navy admiral
- Charles Laverock Lambe (1875-1953), Royal Air Force air marshal
- John Lambe (circa 1545-1628), English astrologer
- John Lambe (M5 Rapist) (born 1944), English criminal
- Lawrence Lambe (1849-1934), Canadian palaeontologist
- Reggie Lambe (born 1991), Bermudian professional footballer
Lambe is also the name of a letter in the Tengwar script.
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