IHC may refer to:
- IHC New Zealand, a national organisation for the support of intellectually handicapped persons
- Immunohistochemistry
- Institute for Human Continuity, a viral marketing campaign for the film 2012
- Intelligent Home Control, home automation and control system
- Interagency Hotshot Crew, a Type 1 handcrew of wildland firefighters
- Intermountain Health Care
- International Harvester Corporation
- International Humanitarian City
- Intrahepatic cholestasis
- Ironheart Crown, a mixed martial arts organization in the US