Genetic association is the occurrence, more often than can be readily explained by chance, of two or more traits in a population of individuals, of which at least one trait is known to be genetic.
Studies of genetic association aim to test whether single-locus alleles or genotype frequencies (or more generally, multilocus haplotype frequencies) differ between two groups of individuals (usually diseased subjects and healthy controls). Genetic association studies are based on the principle that genotypes can be compared "directly", i.e. with the sequences of the actual genomes.
Other articles related to "genetic association, association, genetics, genetic":
... There are many computer packages for analyzing genetic association, such as UNPHASED, WHAP, FBAT, Merlin, PLINK, and Golden Helix's HelixTree Software ... However simple genotypic or allelic association with a dichotomous trait can be measured using the chi-squared test for significance ...
... See also Genetic association One area in which population categories can be important considerations in genetics research is in controlling for ... Association studies can produce spurious results if cases and controls have differing allele frequencies for genes that are not related to the disease being studied ... Population genetic substructure also can aid genetic association studies ...
Famous quotes containing the words association and/or genetic:
“An association of men who will not quarrel with one another is a thing which has never yet existed, from the greatest confederacy of nations down to a town meeting or a vestry.”
—Thomas Jefferson (17431826)
“Man is not merely the sum of his masks. Behind the shifting face of personality is a hard nugget of self, a genetic gift.... The self is malleable but elastic, snapping back to its original shape like a rubber band. Mental illness is no myth, as some have claimed. It is a disturbance in our sense of possession of a stable inner self that survives its personae.”
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