Deleterious

  • (adj): Harmful to living things.
    Example: "Deleterious chemical additives"
    Synonyms: hurtful, injurious

Some articles on deleterious:

Evolution Of Sexual Reproduction - Deleterious Mutation Clearance
... that the majority of non-neutral mutations are deleterious, which means that they will cause a decrease in the organism's overall fitness ... If a mutation has a deleterious effect, it will then usually be removed from the population by the process of natural selection ... There are two main hypotheses which explain how sex may act to remove deleterious genes from the genome ...
Inbreeding Depression and Natural Selection
... Natural selection cannot effectively remove all deleterious recessive genes from a population for several reasons ... First, deleterious genes arise constantly through mutation within a population ... occurs frequently, most offspring will have some deleterious traits, so few will be more fit for survival than the others ...
Nearly Neutral Theory Of Molecular Evolution - Origins of The Nearly Neutral Theory
... time, Tomoko Ohta proposed that most amino acid substitutions are slightly deleterious while noncoding DNA substitutions are more neutral ... the theory that most mutation events at the molecular level are slightly deleterious rather than strictly neutral ... the negative effect on the fitness of a population due to deleterious mutations shifts back to an original value when a mutation reaches fixation ...
Inbreeding - Results
... Inbreeding may result in a far higher phenotypic expression of deleterious recessive genes within a population than would normally be expected ... bottleneck caused by purposeful (assortative) breeding or natural environmental factors, the deleterious inherited traits are culled ... may result in the formation of race or even speciation, as the inbreeding first removes many deleterious genes, and allows expression of genes that ...
Evolution Of Sexual Reproduction - Deleterious Mutation Clearance - Removal of Deleterious Genes
... It assumes that the majority of deleterious mutations are only slightly deleterious, and affect the individual such that the introduction of each additional mutation ... Kondrashov argues that the slightly deleterious nature of mutations means that the population will tend to be composed of individuals with a small number of mutations ... Sex will act to recombine these genotypes, creating some individuals with fewer deleterious mutations, and some with more ...