In heart, in addition to the MM-CK homodimer also the heterodimer consisting of one muscle (MM-CK) and one brain-type (MB-CK) subunit is expressed. This latter is an important serum marker for myocardial infarction, for it is released from damaged myocardial cells into the blood where it can be detected by clinical chemistry. Since no other organ than cardiac muscle expresses significant levels of MB-CK, this clinical test is still fairly reliable, together with troponin-T, for diagnosing a myocardial infarction.
Read more about this topic: CKM (gene)
Other articles related to "clinical significance":
... A study by Cedric F ... Garland and Frank C ...
Famous quotes containing the word significance:
“To grasp the full significance of life is the actors duty, to interpret it is his problem, and to express it his dedication.”
—Marlon Brando (b. 1924)