Most testicular germ cell tumors have too many chromosomes, and most often they are triploid to tetraploid. An isochromosome 12p (the short arm of chromosome 12 on both sides of the same centromere) is present in about 80% of the testicular cancers, and also the other cancers usually have extra material from this chromosome arm through other mechanisms of genomic amplification.
Read more about this topic: Testicular Cancer
Other articles related to "genetic defects, defect, genetic, defects":
... of that, may have suffered from several genetic defects that contributed to his early death ... on twin copies of harmful genes, which is why children of incest more commonly manifest genetic defects ... It is suspected he also had a partially cleft palate, another congenital defect ...
... Genetic abnormalities like Down syndrome and spina bifida have been common explanations ... People afflicted with spina bifida in particular present developmental defects that coincide with the were-jaguar characteristics ...
... Certain genetic disorders have been found in Yorkshire Terriers, including distichiasis, hydrocephalus, hypoplasia of dens, Legg–Calvé–Perthes syndrome, luxating patella, portosystemic shunt, retinal dysplasia ... The following are among the most common congenital defects that affect Yorkies ... Luxating patellas (slipping kneecaps) are another common defect considered to be genetic in Yorkies, although it may also be caused by an accidental fall ...
Famous quotes containing the words defects and/or genetic:
“The East is the hearthside of America. Like any home, therefore, it has the defects of its virtues. Because it is a long-lived-in house, it bursts its seams, is inconvenient, needs constant refurbishing. And some of the family resources have been spent. To attain the privacy that grown-up people find so desirable, Easterners live a harder life than people elsewhere. Today it is we and not the frontiersman who must be rugged to survive.”
—Phyllis McGinley (19051978)
“We cannot think of a legitimate argument why ... whites and blacks need be affected by the knowledge that an aggregate difference in measured intelligence is genetic instead of environmental.... Given a chance, each clan ... will encounter the world with confidence in its own worth and, most importantly, will be unconcerned about comparing its accomplishments line-by-line with those of any other clan. This is wise ethnocentricism.”
—Richard Herrnstein (19301994)