Testicular Cancer - Genetic Defects

Genetic Defects

Most testicular germ cell tumors have too many chromosomes, and most often they are triploid to tetraploid. An isochromosome 12p (the short arm of chromosome 12 on both sides of the same centromere) is present in about 80% of the testicular cancers, and also the other cancers usually have extra material from this chromosome arm through other mechanisms of genomic amplification.

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Other articles related to "genetic defects, defect, genetic, defects":

Tutankhamun - Life - Probable Product of Incest
... of that, may have suffered from several genetic defects that contributed to his early death ... on twin copies of harmful genes, which is why children of incest more commonly manifest genetic defects ... It is suspected he also had a partially cleft palate, another congenital defect ...
Were-jaguar - Origins - Genetic Defects
... Genetic abnormalities like Down syndrome and spina bifida have been common explanations ... People afflicted with spina bifida in particular present developmental defects that coincide with the were-jaguar characteristics ...
Yorkshire Terrier - Health - Teeth - Genetic Defects
... Certain genetic disorders have been found in Yorkshire Terriers, including distichiasis, hydrocephalus, hypoplasia of dens, Legg–Calvé–Perthes syndrome, luxating patella, portosystemic shunt, retinal dysplasia ... The following are among the most common congenital defects that affect Yorkies ... Luxating patellas (slipping kneecaps) are another common defect considered to be genetic in Yorkies, although it may also be caused by an accidental fall ...

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