RNA Polymerase

RNA polymerase (RNAP or RNApol), also known as DNA-dependent RNA polymerase, is an enzyme that produces RNA. In cells, RNAP is necessary for constructing RNA chains using DNA genes as templates, a process called transcription. RNA polymerase enzymes are essential to life and are found in all organisms and many viruses. In chemical terms, RNAP is a nucleotidyl transferase that polymerizes ribonucleotides at the 3' end of an RNA transcript.

Read more about RNA PolymeraseHistory, Control of Transcription, RNA Polymerase Action, RNA Polymerase in Bacteria, RNA Polymerase in Eukaryotes, RNA Polymerase in Archaea, RNA Polymerase in Viruses, RNA Polymerase Purification

Other articles related to "rna polymerase, rna, polymerase":

RNA Polymerase Purification
... RNA polymerase can be isolated in the following ways By a phosphocellulose column ... By glycerol gradient centrifugation ...
RNA Polymerase II Holoenzyme - Holoenzyme Stability
... RNA polymerase II holoenzyme stability determines the number of base pairs that can be transcribed before the holoenzyme loses its ability to transcribe ... The length of the CTD is essential for RNA polymerase II stability ... RNA polymerase II stability has been shown to be regulated by post-translation proline hydroxylation ...
Tethered Particle Motion - History
... In their research, they attached RNA polymerase to the surface, and gold beads were attached to one end of the DNA molecules ... In the beginning, the RNA polymerase "captures" the DNA near the gold bead ... During the transcription, the DNA "slides" on the RNA polymerase so the distance between the RNA polymerase and the gold bead (the tether length)is increased ...
Amanullin - Toxicology
... Like other amatoxins, amanullin is an inhibitor of RNA polymerase II ... has a species dependent and specific attraction to the enzyme RNA polymerase II ... Upon ingestion, it binds to the RNA polymerase II enzyme, effectively causing cytolysis of hepatocytes (liver cells) ...
TAF1B
... TATA box-binding protein-associated factor RNA polymerase I subunit B is an enzyme that in humans is encoded by the TAF1B gene ... Initiation of transcription by RNA polymerase I requires the formation of a complex composed of the TATA-binding protein (TBP) and three TBP-associated ... This complex, known as SL1, binds to the core promoter of ribosomal RNA genes to position the polymerase properly and acts as a channel for regulatory signals ...