Polymerases

Some articles on polymerases, polymerase:

DNA Repair Mechanisms - Translesion Synthesis
... It involves switching out regular DNA polymerases for specialized translesion polymerases (i.e ... DNA polymerase IV or V, from the Y Polymerase family), often with larger active sites that can facilitate the insertion of bases opposite damaged nucleotides ... The polymerase switching is thought to be mediated by, among other factors, the post-translational modification of the replication processivity factor PCNA ...
Transcription (genetics) - Transcription Factories
... Such sites can be visualized by allowing engaged polymerases to extend their transcripts in tagged precursors (Br-UTP or Br-U) and immuno-labeling the tagged nascent RNA ... in situ hybridization or marked by antibodies directed against polymerases ... nucleoplasm of a HeLa cell, among which are ~8,000 polymerase II factories and ~2,000 polymerase III factories ...
Deoxyribonucleic Acid - Interactions With Proteins - DNA-modifying Enzymes - Polymerases
... Polymerases are enzymes that synthesize polynucleotide chains from nucleoside triphosphates ... As a consequence, all polymerases work in a 5′ to 3′ direction ... the incoming nucleoside triphosphate base-pairs to the template this allows polymerases to accurately synthesize the complementary strand of their template ...
Processivity - Polymerase Processivities
... Multiple DNA polymerases have specialized roles in the DNA replication process ... its entire genome from a single replication fork, the polymerase DNA Pol III is the enzyme primarily responsible for DNA replication and forms a replication ... In eukaryotes, which have a much higher diversity of DNA polymerases, the low-processivity initiating enzyme is called Pol α, and the high-processivity extension enzymes are Pol δ and Pol ε ...
POLRMT - Function
... This gene encodes a mitochondrial DNA-directed RNA polymerase ... as the three nuclear DNA-directed RNA polymerases, it is more closely related to RNA polymerases of bacteriophage and mitochondrial polymerases of lower eukaryotes ...