Opioid Receptors

Some articles on opioid receptors, opioid, receptors, opioid receptor, opioids, receptor:

Acetomorphine - Pharmacology
6-MAM), and then to morphine, which bind to μ-opioid receptors, resulting in the drug's euphoric, analgesic (pain relief), and anxiolytic (anti-anxiety) effects ... Both morphine and 6-MAM are μ-opioid agonists that bind to receptors present throughout the brain, spinal cord, and gut of all mammals ... The μ-opioid receptor also binds endogenous opioid peptides such as β-endorphin, Leu-enkephalin, and Met-enkephalin ...
Opioid - Adverse Effects - Managing Adverse Effects
... does not cross the blood–brain barrier, so blocks opioid emetic action in the chemoreceptor trigger zone without adverse central anti-dopaminergic effects (not available in the U.S.) Some antihistamines with ... over 5–7 days, but if troublesome, switching to an alternative opioid often helps ... Certain opioids such as fentanyl, morphine and diamorphine (heroin) tend to be particularly sedating, while others such as oxycodone, tilidine and meperidine (pethidine) tend to produce comparatively less ...
Opioid - Classification
... There are a number of broad classes of opioids Natural opiates alkaloids contained in the resin of the opium poppy, primarily morphine, codeine, and thebaine, but not papaverine and noscapine which ... Salvinorin A, found naturally in the Salvia divinorum plant, is a kappa-opioid receptor agonist ... acetylpropionylmorphine, dibenzoylmorphine, diacetyldihydromorphine Semi-synthetic opioids created from either the natural opiates or morphine esters, such as hydromorphone, hydrocodone, oxycodone, oxymorphone ...
Methylnaltrexone - Development
... Research on opioids which would target only the sub-types of receptors associated with pain relief and not with side effects had seen little success ... Considering drugs such as loperamide, which acted on the opioid receptors in the gut without acting on the central nervous system, Goldberg proposed a targeted opioid receptor antagonist ... Thousands of opioid-like molecules had been synthesized by pharmaceutical companies looking for the better analgesic - and many of those with no pain relieving properties had been shelved ...
Opioid Antagonist
... An opioid antagonist is a receptor antagonist that acts on opioid receptors ... Naloxone and naltrexone are commonly used opioid antagonist drugs which are competitive antagonists that bind to the opioid receptors with higher affinity than agonists but do not activate the receptors ... This effectively blocks the receptor, preventing the body from responding to opiates and endorphins ...

Famous quotes containing the word receptors:

    Our talk of external things, our very notion of things, is just a conceptual apparatus that helps us to foresee and control the triggerings of our sensory receptors in the light of previous triggering of our sensory receptors.
    Willard Van Orman Quine (b. 1908)