Management of Baldness - Research - Genetics

Genetics

In February 2008 researchers at the University of Bonn announced they have found the genetic basis of two distinct forms of inherited hair loss, opening a broad path to treatments for baldness. They found that a gene, P2RY5, causes a rare, inherited form of hair loss called hypotrichosis simplex. It is the first receptor in humans known to play a role in hair growth. The fact that any receptor plays a specific role in hair growth was previously unknown to scientists and they are now attempting to gather more genetic and biological data.

In May 2009, researchers in Japan identified a gene, SOX21, that appears to determine cyclical hair loss in mice. The researchers also believe it may be responsible for hair loss, or alopecia, in people.

Through 2006, Curis and Procter & Gamble spent $1,000,000 on a hair growth program focused on the potential development of a topical hedgehog agonist for hair growth disorders such as male pattern baldness and female hair loss. Because the agent did not meet the proper safety standards., the hair loss research program was shut down in May 2007

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