Lagging Strand

Some articles on strands, strand, lagging strand, lagging strands:

DNA Replication - Replication Process - Origins
... "origins", which are targeted by proteins that separate the two strands and initiate DNA synthesis ... These initiators recruit other proteins to separate the strands and initiate replication forks ... recruit other proteins and form the pre-replication complex, which separate the DNA strands at the origin and forms a bubble ...
Antiparallel (biochemistry) - Nucleic Acids - DNA Replication
... the 5' carbon is located at the top of the leading strand, and the 3' carbon is located at the lower section of the lagging strand ... structure of DNA is important in DNA replication because it replicates the leading strand one way and the lagging strand the other way ... During DNA replication the leading strand is replicated continuously whereas the lagging strand is replicated in segments known as Okazaki fragments ...
Replisome - Solving The Challenges of DNA Replication - Priming The Leading and Lagging Strands
... From both a structural and chemical perspective, a single strand of DNA by itself (and the associated single strand binding proteins) is not suitable for polymerisation ... solve this problem by creating an RNA primer on the leading and lagging strands ... The leading strand is primed once, and the lagging strand is primed approximately every 1000 (+/- 200) base pairs (one primer for each Okazaki fragment on the lagging strand) ...
DnaA - Function
... Single-strand binding proteins (SSBs) stabilize the single DNA strands in order to maintain the replication bubble ... DnaB is a 5'→3' helicase, so it travels on the lagging strand ... to form the only primer for the leading strand and to add RNA primers on the lagging strand ...

Famous quotes containing the words strand and/or lagging:

    The annals of this voracious beach! who could write them, unless it were a shipwrecked sailor? How many who have seen it have seen it only in the midst of danger and distress, the last strip of earth which their mortal eyes beheld. Think of the amount of suffering which a single strand had witnessed! The ancients would have represented it as a sea-monster with open jaws, more terrible than Scylla and Charybdis.
    Henry David Thoreau (1817–1862)

    Wait, Kate! You skate at such a rate
    You leave behind your skating mate.
    Your splendid speed won’t you abate?
    He’s lagging far behind you, Kate.
    David Daiches (b. 1912)