Kinase

In biochemistry, a kinase is a type of enzyme that transfers phosphate groups from high-energy donor molecules, such as ATP, to specific substrates, a process referred to as phosphorylation. Kinases are part of the larger family of phosphotransferases. Kinases are not to be confused with phosphorylases, which carry out phosphorolysis, the breaking of a bond using an inorganic phosphate group; or with phosphatases, which remove phosphate groups.

Read more about Kinase:  Types

Other articles related to "kinases, kinase":

SUGEN - Shutdown and Legacy
... to SU11248, known as SU14813, and programs on Met and PAK kinases ... Sugen also generated extensive basic research on kinase biology, including the publication of almost 300 research papers, the definition of the human kinome, and the discovery of over 140 human kinase genes ... Sugen alumni have gone on to major positions in other pharmaceutical and kinase-focused companies ...
LATS1
... Serine/threonine-protein kinase LATS1 is an enzyme that in humans is encoded by the LATS1 gene ... The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis ... form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A ...
Kinase - Types
... One of the largest groups of kinases are protein kinases, which act on and modify the activity of specific proteins ... Kinases are used extensively to transmit signals and control complex processes in cells ... More than five hundred different kinases have been identified in humans ...
LMTK2 - Function
... The LMTK2 enzyme belongs to both the protein kinase and the tyrosine kinase families ... helices and a long C-terminal cytoplasmic tail with serine/threonine/tyrosine kinase activity ... is itself also phosphorylated when interacting with cyclin-dependent kinase 5 (cdk5)/p35 complex ...
LY294002
... It is a potent inhibitor of phosphoinositide 3-kinases (PI3Ks) ... Two of these are the proto-oncogene serine/threonine-protein kinase (PIM1) and the phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform ... than wortmannin, another well-known PI3 kinase inhibitor However, LY294002 is a reversible inhibitor of PI3K whereas wortmannin acts irreversibly ...