The reason that glucose, and not another monosaccharide such as fructose, is so widely used in organisms is not clearly understood. One reason might be that glucose has a lower tendency, relative to other hexose sugars, to react non-specifically with the amino groups of proteins. This reaction (glycation) reduces or destroys the function of many enzymes. The low rate of glycation is due to glucose's preference for the less reactive cyclic isomer. Nevertheless, many of the long-term complications of diabetes (e.g., blindness, renal failure, and peripheral neuropathy) are probably due to the glycation of proteins or lipids. In contrast, enzyme-regulated addition of glucose to proteins by glycosylation is often essential to their function.
Read more about this topic: Glucose
Other articles related to "function":
... Let f be a continuous real-valued function defined on a closed interval ... Let F be the function defined, for all x in, by Then, F is continuous on, differentiable on the open interval (a, b), and for all x in (a, b) ... Let f be a real-valued function defined on a closed interval that admits an antiderivative g on ...
... is the statement that differentiation and integration are inverse operations if a continuous function is first integrated and then differentiated, the original function is ... integrals by using an antiderivative of the function to be integrated ...
... In general, an integral over a set E of a function f is written Here x need not be a real number, but can be another suitable quantity, for instance, a ... as the definite integral of a positive function of one variable represents the area of the region between the graph of the function and the x-axis, the double integral of a positive ... via the triple integral — the integral of a function in three variables — of the constant function f(x, y, z) = 1 over the above mentioned region between ...
Famous quotes containing the word function:
“Any translation which intends to perform a transmitting function cannot transmit anything but informationhence, something inessential. This is the hallmark of bad translations.”
—Walter Benjamin (18921940)
“It is not the function of our Government to keep the citizen from falling into error; it is the function of the citizen to keep the Government from falling into error.”
—Robert H. [Houghwout] Jackson (18921954)
“The function of muscle is to pull and not to push, except in the case of the genitals and the tongue.”
—Leonardo Da Vinci (14251519)