Basement Membrane

The basement membrane is a thin sheet of fibers that underlies the epithelium, which lines the cavities and surfaces of organs including skin, or the endothelium, which lines the interior surface of blood vessels.

Read more about Basement Membrane:  Composition, Function and Importance, Diseases

Other articles related to "basement membrane, basement membranes":

Loin Pain Hematuria Syndrome - Diagnosis - Relation To Thin Basement Membrane Disease
... A thin glomerular basement membrane, as in thin basement membrane disease, is proposed to be the characteristic finding on renal biopsy, but not part of the ...
Perlecan - Disease Association - Diabetes and Cardiovascular Disease
... Decreased perlecan in the glomerular basement membrane has a central role in the development of diabetic albuminuria. 80% of diabetes-associated deaths involve some form of atherosclerotic complication, and the basement membrane of endothelia has been implicated in the. 2-10-fold increase in expression of other basement membrane proteoglycans ...
Acute Proliferative Glomerulonephritis - Pathophysiology
... an infection) become lodged in the glomerular basement membrane below the podocyte foot processes ... Complement activation leads to destruction of the basement membrane ... nephrotoxic streptococcal infections have a high affinity for basement membrane proteins, giving rise to particularly severe, long lasting antibody response ...
Basement Membrane - Diseases
... Some diseases result from a poorly functioning basement membrane ... Genetic defects in the collagen fibers of the basement membrane cause Alport syndrome ... Non-collagenous domain basement membrane collagen type IV is autoantigen (target antigen) of autoantibodies in the autoimmune disease Goodpasture's syndrome ...
Perlecan - Disease Association - Cancer
... Since the basement membrane is the first obstacle in the way of extravasating carcinoma cells, the functions of perlecan in this process are multiple ... Perlecan staining is lost in ovarian basement membrane that has been breached by an invasive adenocarcinoma, which is in contrast to perlecan staining in the basement membranes of normal ... This is consistent with other results showing loss of perlecan in basement membranes affected by invasive cervical cancer spreading to the pelvic lymph nodes, which comes as no surprise due to the ...