As a food additive, zinc oxide is on the U.S. FDA's list of generally recognized as safe, or GRAS, substances.
Zinc oxide itself is non-toxic; however it is hazardous to inhale zinc oxide fumes, as generated when zinc or zinc alloys are melted and oxidized at high temperature. This problem occurs while melting brass because the melting point of brass is close to the boiling point of zinc. Exposure to zinc oxide in the air, which also occurs while welding galvanized (zinc plated) steel, can result in a nervous malady called metal fume fever. For this reason, typically galvanized steel is not welded, or the zinc is removed first.
Read more about this topic: Zinc Oxide
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