TYRO3

TYRO3

Identifiers Symbols TYRO3; BYK; Dtk; RSE; Sky; Tif External IDs OMIM: 600341 MGI: 104294 HomoloGene: 4585 ChEMBL: 5314 GeneCards: TYRO3 Gene EC number 2.7.10.1

Gene Ontology
Molecular function	• protein tyrosine kinase activity • transmembrane receptor protein tyrosine kinase activity • receptor signaling protein tyrosine kinase activity • protein binding • ATP binding • phosphatidylinositol 3-kinase binding • protein heterodimerization activity
Cellular component	• nucleus • nuclear envelope • endoplasmic reticulum membrane • integral to plasma membrane
Biological process	• natural killer cell differentiation • cell adhesion • signal transduction • spermatogenesis • phosphatidylinositol 3-kinase cascade • forebrain cell migration • signal transduction by phosphorylation • platelet activation • secretion by cell • negative regulation of toll-like receptor signaling pathway • substrate adhesion-dependent cell spreading • ovulation cycle • apoptotic cell clearance • protein kinase B signaling cascade • negative regulation of neuron apoptotic process • negative regulation of innate immune response • protein autophosphorylation • negative regulation of inflammatory response • negative regulation of lymphocyte activation • vagina development • neuron homeostasis • platelet aggregation
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 7301 22174 Ensembl ENSG00000092445 ENSMUSG00000027298 UniProt Q06418 P55144 RefSeq (mRNA) NM_006293 NM_019392 RefSeq (protein) NP_006284 NP_062265 Location (UCSC) Chr 15:
41.85 – 41.87 Mb Chr 2:
119.8 – 119.82 Mb PubMed search

Tyrosine-protein kinase receptor TYRO3 is an enzyme that in humans is encoded by the TYRO3 gene.