Threonine

Threonine (abbreviated as Thr or T) is an α-amino acid with the chemical formula HO2CCH(NH2)CH(OH)CH3. Its codons are ACU, ACA, ACC, and ACG. This essential amino acid is classified as polar. Together with serine, threonine is one of two proteinogenic amino acids bearing an alcohol group (tyrosine is not an alcohol but a phenol, since its hydroxyl group is bonded directly to an aromatic ring, giving it different acid/base and oxidative properties). It is also one of two common amino acids that bear a chiral side chain, along with isoleucine.

The threonine residue is susceptible to numerous posttranslational modifications. The hydroxy side-chain can undergo O-linked glycosylation. In addition, threonine residues undergo phosphorylation through the action of a threonine kinase. In its phosphorylated form, it can be referred to as phosphothreonine.

Read more about ThreonineHistory, Stereoisomerism, Biosynthesis, Metabolism, Sources

Other articles related to "threonine":

PIM1
2.7.11.1 Gene Ontology Molecular function • protein serine/threonine kinase activity • protein binding • ATP binding • transcription factor binding • manganese ion binding • ribosomal small subunit ... Pim-1 is a proto-oncogene which encodes for the serine/threonine kinase of the same name ...
Beta Adrenergic Receptor Kinase - βARK Activation
... on, it will phosphorylate serine and threonine residues on βARK ... (step 7) βARK, itself a serine/threonine kinase, will then phosphorylate serine and threonine resides on the β-adrenergic receptor itself ...
L-threonine 3-dehydrogenase
... In enzymology, a L-threonine 3-dehydrogenase (EC 1.1.1.103) is an enzyme that catalyzes the chemical reaction L-threonine + NAD+ L-2-amino-3-oxobutanoat ... Other names in common use include L-threonine dehydrogenase, threonine 3-dehydrogenase, and threonine dehydrogenase ... This enzyme participates in glycine, serine and threonine metabolism ...
L-threonine Dehydrogenase
... L-Threonine dehydrogenase is an enzyme that facilitates the catabolism of threonine ... It catalyses its conversion to glycine via 2-amino-3-ketobutyrate with concomitant reduction of NAD+ ...
Threonine - Sources
... Foods high in threonine include cottage cheese, poultry, fish, meat, lentils, and sesame seeds ... Racemic threonine can be prepared from crotonic acid by alpha-functionalization using mercury(II) acetate ...