Pyruvate Kinase

Pyruvate kinase (EC: 2.7.1.40) is an enzyme involved in glycolysis. It catalyzes the transfer of a phosphate group from phosphoenolpyruvate (PEP) to ADP, yielding one molecule of pyruvate and one molecule of ATP.

Read more about Pyruvate Kinase:  Reaction, Regulation, Deficiency, Role in Gluconeogenesis, Alternatives

Other articles related to "pyruvate kinase, pyruvate":

PKM2
... EC number 2.7.1.40 Gene Ontology Molecular function • magnesium ion binding • pyruvate kinase activity • protein binding • ATP binding • potassium ion ... is an isoenzyme of the glycolytic enzyme pyruvate kinase ... different metabolic functions of the tissues, different isoenzymes of pyruvate kinase are expressed ...
PKM2 - The Pyruvate Kinase Reaction
... Pyruvate kinase catalyzes the last step within glycolysis, the dephosphorylation of phosphoenolpyruvate to pyruvate and is responsible for net ATP production within the glycolytic sequence ... respiration, energy regeneration by pyruvate kinase is independent from oxygen supply and allows survival of the organs under hypoxic conditions often found in solid ...
Pyruvate Kinase - Alternatives
... A reversible enzyme with a similar function, Pyruvate phosphate dikinase (PPDK), is found in some bacteria and has been transferred to a number of anaerobic eukaryote groups (for example ... In some cases, the same organism will have both Pyruvate kinase and PPDK ...
Tumor M2-PK - Tetrameric and Dimeric PKM2
... Pyruvate kinase catalyzes the last step within the glycolytic sequence, the dephosphorylation of phosphoenolpyruvate to pyruvate and is responsible for net energy production within the glycolytic pathway ... upon the different metabolic functions of the tissues, different isoenzymes of pyruvate kinase are expressed ... M2-PK (PKM2) is the predominant pyruvate kinase isoform in proliferating cells, such as fibroblasts, embryonic cells and adult stem cells and most human tissue, including lung, bladder, kidney and thymus M2-PK is ...
Phosphoenolpyruvic Acid - In Glycolysis
... Metabolism of PEP to pyruvate by pyruvate kinase (PK) generates 1 molecule of adenosine triphosphate (ATP) via substrate-level phosphorylation. 2-phospho--glycerate Enolase phosphoenolpyruvate Pyruvate kinase pyruvate H2O ADP ATP H2O Enolase Pyruvate kinase Compound C00631 at KEGG Pathway Database ...