In molecular biology, the PRINTS database is a collection of so-called "fingerprints": it provides both a detailed annotation resource for protein families, and a diagnostic tool for newly-determined sequences. A fingerprint is a group of conserved motifs taken from a multiple sequence alignment - together, the motifs form a characteristic signature for the aligned protein family. The motifs themselves are not necessarily contiguous in sequence, but may come together in 3D space to define molecular binding sites or interaction surfaces. The particular diagnostic strength of fingerprints lies in their ability to distinguish sequence differences at the clan, superfamily, family and subfamily levels. This allows fine-grained functional diagnoses of uncharacterised sequences, allowing, for example, discrimination between family members on the basis of the ligands they bind or the proteins with which they interact, and highlighting potential oligomerisation or allosteric sites.
PRINTS is a founding partner of the integrated resource, InterPro, a widely used database of protein families, domains and functional sites.
Other articles related to "print, prints":
2, 1885 - February 14, 1962) was a Japanese print publisher and the driving force behind the Japanese printmaking movement known as shin-hanga ("new prints") ... which gave him an opportunity to learn about exporting art prints ... Watanabe employed highly skilled carvers and printers, and commissioned artists to design prints that combined traditional Japanese techniques with elements of contemporary Western painting, such as perspective ...
... They specialized in very small finely detailed prints, some no larger than a postage stamp ... The size and subject matter of the prints shows that they were designed for a market of collectors who would keep them in albums, of which a number have survived. 1506–7, probably following the example of Italian niello prints, although their size was in fact no smaller than the bottom end of the very cheap devotional woodcuts made throughout the 15th century ...
1861-1862 - Provisional prints (coarse and fine prints) (Scott 8-15) 1862-1867 - Consecutive Athens prints (Scott 16-22) 1867-1869 1873 for the 80 lepta - Cleaned plates issues (Scott ...
... as the need arises in order to create special prints in celebration of events relating to his band, The Avett Brothers ... Scott specializes in creating relief prints, a skill that he acquired at ECU under the direction of professor Michael Elhbeck ... These prints are renowned among the fans of The Avett Brothers both for their sentimental and artistic value ...
Famous quotes containing the word prints:
“An editor is someone who separates the wheat from the chaff and then prints the chaff.”
—Adlai Stevenson (19001965)
“My wife never quite forgets to put flowers in vases,
Bizarre prints in the most unusual places,
Give teas for poets, wear odoriferous furs.
An awful blooming is hers.”
—Gwendolyn Brooks (b. 1917)
“Unfortunately, it is much easier to shut ones eyes to good than to evil. Pain and sorrow knock at our doors more loudly than pleasure and happiness; and the prints of their heavy footsteps are less easily effaced.”
—Thomas Henry Huxley (182595)