Platelet - Discovery

Discovery

Although red blood cells had been known since van Leeuwenhoek (1632–1723), the German anatomist Max Schultze (1825–1874) was the first to describe platelets. He described "spherules" that were much smaller than red blood cells and that occasionally clumped and were found in collections of fibrous material.

Giulio Bizzozero (1846–1901), building on Schultze's findings, used "living circulation" to study blood cells of amphibians microscopically in vivo. He is especially noted for discovering that platelets clump at the site of blood vessel injury, a process that precedes the formation of a blood clot. This observation confirmed the role of platelets in coagulation.

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