Parasitophorous Vacuole

Plasmodium Falciparum Biology - Erythrocytic Stage - Egress From The Erythrocyte
... of the merozoites, the now functionless digestive vacuole is also released ... On ingestion the digestive vacuoles induce a vigorous respiratory burst which drives the cells into a state of functional exhaustion, blunting production of reactive oxygen species and microbicidal activity ... It is secreted together with other SERAs into the parasitophorous vacuole in an infected erythrocyte where it is cleaved into three fragments an N-terminal ...

Plasmodium Falciparum Biology - Cell Biology - Apical Complex
... is involved in formation and maintenance of the parasitophorous vacuole ... distributed in the schizonts' cytoplasm but not in the parasitophorous vacuole ... It also appears that the formation of the junction and parasitophorous vacuole are molecularly distinct steps in the invasion process ...

Plasmodium Falciparum Biology - Liver Stage - Molecular Biology of Liver Stages
... It is thought to be localised to the membrane of the parasitophorous vacuole of the infected cell ... LISP2 is carried first to the parasitophorous vacuole and subsequently transported to the cytoplasm and nucleus of host hepatocytes ... to be important in the formation of the parasitophorous vacuole membrane in the liver ...

Plasmodium Falciparum Biology - Cell Biology - Parasitophorous Vacuole
... falciparum resides inside the parasitophorous vacuole ... The proteins originating in the parasite pass through the membrane of the parasitophorous vacuole and are transported to the cytoplasm or membrane of the erythrocyte ... coalesce to form a single acidic digestive vacuole (pH 4.5 - 5.5) that is then fed by haemoglobin containing vesicles ...