Padmanabha may refer to:
- Padmanabha (Lotus-navel), one of the aspects of Vishnu or God with a lotus issuing from his navel on which Brahma sits. See also: Garbhodaksayi Vishnu
- Padmanabha Swamy, the presiding deity at the Padmanabhaswamy Temple in Thiruvananthapuram, Kerala
- Padmanabhapuram, a town in Kanyakumari district, Tamil Nadu, India
- Anantha Padmanabha Swamy Temple - Vikarabad, Andhra Pradesh