Maintenance of Heart Structure
NRG-1 treatment of adult rat ventricular myocytes stimulate the formation of a multiprotein complex between ErbB2, FAK, and p130(CAS), which modulates the restoration of cell–cell contacts between isolated myocytes, allowing for synchronous beating. Furthermore FAK is also involved in the maintenance of sarcomeric organization, cell survival, and myocyte–myocyte interactions. The sarcomeric effects of NRG-1 protects myocytes against structural disarray induced by stressors, including cytotoxic agents.
Read more about this topic: Neuregulin 1, Functions in The Heart
Famous quotes containing the words maintenance of, maintenance, heart and/or structure:
“It is an injustice that an old, broken, half-dead father should enjoy alone, in a corner of his hearth, possessions that would suffice for the advancement and maintenance of many children.”
—Michel de Montaigne (1533–1592)
“War is in truth a disease in which the juices that serve health and maintenance are used for the sole purpose of nourishing something foreign, something at odds with nature.”
—Johann Wolfgang Von Goethe (1749–1832)
“Old women even forget how to love their sons. The heart gets worn out, Monsieur.”
—Albert Camus (1913–1960)
“Communism is a proposition to structure the world more reasonably, a proposition for changing the world. As such, we have to analyze it and, if we deem it reasonable, act upon it.”
—Friedrich Dürrenmatt (1921–1990)