Negative selection may refer to:
- In biology:
- Negative selection (natural selection), in natural selection it refers to the selective removal of rare alleles that are deleterious
- Negative selection (artificial selection), in artificial selection it refers to where negative, rather than positive, traits of a species are selected for
- In politics:
- Negative selection (politics), is a process that occurs in rigid hierarchies, most notably dictatorships
- In immunology:
- Negative selection (immunology) T-cells that recognize self MHC molecules (and peptides) with high affinity are deleted from the repertoire of cells. Central tolerance is produced. Avoids auto-immunity. Occurs after positive selection.
Famous quotes containing the words negative and/or selection:
“Our role is to support anything positive in black life and destroy anything negative that touches it. You have no other reason for being. I don’t understand art for art’s sake. Art is the guts of the people.”
—Elma Lewis (b. 1921)
“Judge Ginsburg’s selection should be a model—chosen on merit and not ideology, despite some naysaying, with little advance publicity. Her treatment could begin to overturn a terrible precedent: that is, that the most terrifying sentence among the accomplished in America has become, “Honey—the White House is on the phone.””
—Anna Quindlen (b. 1952)