Neuropathic Pain
Hyperalgesia and allodynia are examples of neuropathic pain. It is thought that the activation of specialized neuronal nociceptors are responsible for hyperalgesia. Studies suggest that hyperalgesia and allodynia are set off and sustained by certain groups of mechanosensitive sensory neurons. There is a general consensus among the scientific community that neuropeptides and NMDA receptors are crucial to the initiation of sensitization states such as hyperalgesia and allodynia.
Read more about this topic: Mechanosensation
Famous quotes containing the word pain:
“What is most original in a man’s nature is often that which is most desperate. Thus new systems are forced on the world by men who simply cannot bear the pain of living with what is. Creators care nothing for their systems except that they be unique. If Hitler had been born in Nazi Germany he wouldn’t have been content to enjoy the atmosphere.”
—Leonard Cohen (b. 1934)