US
- US – (i) United States (also (s) ISO 3166 and FIPS 10-4 country code digram)
- USA – (i) United States of America (also (s) ISO 3166 trigram) – United States Army
- USAADAC – (i) U.S. Army Air Defense Artillery Center, Fort Bliss, Texas
- USAARMC – (p) U.S. Army ARMor Center, Fort Knox, Kentucky
- USAAVNC – (p) U.S. Army AViatioN Center, Fort Rucker, Alabama
- USAF – (i) United States Air Force
- USAFSPC – (i) U.S. Air Force Space Command
- USAIC – (i) U.S. Army Infantry Center – U.S. Army Intelligence Center
- USAID – (a/i) United States Agency for International Development
- USAP
- (a) Union Sportive des Arlequins Perpignanais
- (i) United States Antarctic Program
- USAPATRIOT – (i) Uniting and Strengthening America by Providing Appropriate Tools Required to Intercept and Obstruct Terrorism
- USAREUR – (p) United States Army Europe
- USB – (i) Universal Serial Bus
- USC – (i) United States Code – University of South Carolina – University of Southern California
- USCG – (i) United States Coast Guard
- USCINCSPACE – (p) United States Commander in Chief, Space Command
- USD – (i) (U.S.) Under-Secretary of Defense – (s) U.S. dollar (ISO 4217 currency code)
- USD(A&T) – (i) (U.S.) Under-Secretary of Defense (Acquisition and Technology)
- USD(AT&L) – (i) (U.S.) Under-Secretary of Defense for Acquisition, Technology, and Logistics
- USD(C) – (i) (U.S.) Under-Secretary of Defense (Comptroller)
- USDA – (i) United States Department of Agriculture
- USDI – (i) United States Department of the Interior
- USDOE – (i) United States Department of Energy
- USD(P) – (i) (U.S.) Under-Secretary of Defense (Policy)
- USD(P&R) – (i) (U.S.) Under-Secretary of Defense (Personnel & Readiness)
- USDRE – (i) (U.S.) Under-Secretary of Defense for Research and Engineering (1978–1986)
- USEC – (a) United States Enrichment Corporation
- USFL – (i) United States Football League
- USFWS – (i) United States Fish and Wildlife Service
- USGS – (i) United States Geological Survey
- USIA – (i) United States Information Agency
- USJFCOM – (p) United States Joint Forces Command
- USMC – (i) United States Marine Corps
- United States Navy – (i) United States Navy
- USNA – (i) United States National Arboretum – United States Naval Academy
- USNB – (i) United States Naval Base
- USNG – (i) United States National Grid
- USNH – (i) United States Naval Hospital
- USNI – (i) United States Naval Institute
- USNO – (i) U.S. Naval Observatory
- USNOFS – (i) United States Naval Observatory Flagstaff Station
- USNP – (i) United States Newspaper Program
- USNR – (i) United States Navy Reserve
- USNS – (i) United States Naval Ship
- USNY – (a) University of the State of New York (usually pronounced "use-knee")
- USNZ – (i) University Sport New Zealand
- USPS – (i) United States Postal Service
- USPTO – (i) United States Patent and Trademark Office
- USR – (a) Universal System Resources (/usr, directory in a *NIX filesystem), (s) User
- USS – (i) United States ship (sometimes meaningless; see Star Trek)
- USSPACECOM – (p) United States Space Command
- USSR – (i) Union of Soviet Socialist Republics
- UST – (i) Underground Storage Tank
- USTRANSCOM – (p) United States Transportation Command
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