JLC may refer to:
- Jaeger-LeCoultre, a watch and clock manufacturer
- Jamie Lee Curtis, an American actress
- Japan Lutheran Church
- Jenna-Louise Coleman, a British actress
- Jewish Labor Committee
- The John Labatt Centre in London, Ontario
- John Lloyd Cruz, Filipino actor
- Joshua Lawrence Chamberlain, hero of the American Civil War
- John Leggott College A college in North Lincolnshire, England
- Jump, Little Children
- Justin Lee Collins, a British comedian, radio and television presenter