Indole Alkaloids

Indole alkaloids are a class of alkaloids containing a structural moiety of indole; many indole alkaloids also include isoprene groups. Containing more than 4100 known different compounds, it is one of the largest classes of alkaloids. Many of them possess significant physiological activity and some of them are used in medicine. The amino acid tryptophan is the biochemical precursor of indole alkaloids.

Read more about Indole Alkaloids:  History, Classification, Non-isoprenoid Indole Alkaloids, Isoprenoid Indole Alkaloids, Bisindole Alkaloids, Distribution in Nature, Biosynthesis, Physiological Activity, Applications

Other articles related to "indole alkaloids, alkaloids":

Indole Alkaloids - Applications
... Plants and fungi that contain indole alkaloids have a long history of use in traditional medicine ... the plants were joined by pure preparations of indole alkaloids ... Ergot alkaloids ergometrine (ergobazin, ergonovine), ergotamine and their synthetic derivatives (methylergometrine) are applied against uterine bleeding, and ...
Indole Alkaloid - Biosynthesis
... Biogenetic precursor of all indole alkaloids is the amino acid tryptophan ... Biosynthesis of β-carboline alkaloids occurs through the formation of Schiff base from tryptamine and aldehyde (or keto acid) and subsequent intramolecular Mannich reaction, where the C(2 ... In the formation of simple β-carboline alkaloids, such as harmine and harmaline, pyruvic acid acts as the keto acid ...
Indole Alkaloid - Physiological Activity
... Indole alkaloids act on the central and peripheral nervous systems ... Besides, bisindole alkaloids vinblastine and vincristine show antineoplastic effect ... Compared with other ergot alkaloids, ergometrine has a greater selectivity in stimulating the uterus ...
Indole Alkaloid - Applications
... Plants and fungi that contain indole alkaloids have a long history of use in traditional medicine ... Later, the plants were joined by pure preparations of indole alkaloids ... Ergot alkaloids ergometrine (ergobazin, ergonovine), ergotamine and their synthetic derivatives (methylergometrine) are applied against uterine bleeding, and ...

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