Extracellular Matrix

In biology, the extracellular matrix (ECM) is the extracellular part of animal tissue that usually provides structural support to the animal cells in addition to performing various other important functions. The extracellular matrix is the defining feature of connective tissue in animals.

Extracellular matrix includes the interstitial matrix and the basement membrane. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Gels of polysaccharides and fibrous proteins fill the interstitial space and act as a compression buffer against the stress placed on the ECM. Basement membranes are sheet-like depositions of ECM on which various epithelial cells rest.

Read more about Extracellular MatrixRole and Importance, Molecular Components, Cell Adhesion To The ECM, Cell Types Involved in ECM Formation, Extracellular Matrix in Plants, Medical Applications

Other articles related to "extracellular matrix, matrix, extracellular":

LTBP1 (gene)
... Cellular component • proteinaceous extracellular matrixextracellular matrix Biological process • sequestering of TGFbeta in extracellular matrix Sources Amigo ... gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different ...
Extracellular Matrix - Medical Applications
... Extracellular matrix cells have been found to cause regrowth and healing of tissue ... In human fetuses, for example, the extracellular matrix works with stem cells to grow and regrow all parts of the human body, and fetuses can regrow anything that gets damaged in ... Scientists have long believed that the matrix stops functioning after full development ...
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PTK2 - Function
... concentrated in the focal adhesions that form among cells attaching to extracellular matrix constituents ... signal transduction pathways that promote the turn-over of cell contacts with the extracellular matrix, promoting cell migration ... known as focal adhesions, these are multi-protein structures that link the extracellular matrix (ECM) to the cytoplasmic cytoskeleton ...
... COL4A2 Gene Gene Ontology Molecular function • extracellular matrix structural constituent • protein binding Cellular component • extracellular region ...

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