Dyspepsia - Treatment - H. Pylori Connection

H. Pylori Connection

The relationship between H. pylori and functional dyspepsia has been controversial, with several trials finding a benefit and others finding no benefit; a 2003 Cochrane Collaboration review found that treating H. pylori did have a small effect in improving nonulcer dyspepsia symptoms.

More recently, "Helicobacter pylori eradication provided significant benefits to primary care patients with functional dyspepsia." according to a randomized controlled trial. In this trial, the relative benefit ratio of Helicobacter pylori eradication for 50% reduction in symptoms at 12 months was 1.3 and, the relative benefit increase was 34.3%. In populations similar to those in this study which had a rate of benefit as measured by the 50% reduction in symptoms at 12 months of 36.5% without treatment, the number needed to treat is 8.

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