H. Pylori Connection
The relationship between H. pylori and functional dyspepsia has been controversial, with several trials finding a benefit and others finding no benefit; a 2003 Cochrane Collaboration review found that treating H. pylori did have a small effect in improving nonulcer dyspepsia symptoms.
More recently, "Helicobacter pylori eradication provided significant benefits to primary care patients with functional dyspepsia." according to a randomized controlled trial. In this trial, the relative benefit ratio of Helicobacter pylori eradication for 50% reduction in symptoms at 12 months was 1.3 and, the relative benefit increase was 34.3%. In populations similar to those in this study which had a rate of benefit as measured by the 50% reduction in symptoms at 12 months of 36.5% without treatment, the number needed to treat is 8.
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“What is the vanity of the vainest man compared with the vanity which the most modest person possesses when, in connection with nature and the world, he experiences himself as “man”!”
—Friedrich Nietzsche (1844–1900)