A chiller is a machine that removes heat from a liquid via a vapor-compression or absorption refrigeration cycle. This liquid can then be circulated through a heat exchanger to cool air or equipment as required.

Read more about Chiller:  Use in Air Conditioning, Use in Industry, Vapor-compression Chiller Technology, How Absorption Technology Works, Industrial Chiller Selection, Refrigerants

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Chiller - Refrigerants
... A vapor-compression chiller uses a refrigerant internally as its working fluid ... Many refrigerants options are available when selecting a chiller, the application cooling temperature requirements and refrigerant's cooling characteristics ... concern refrigerants, and also affect the future availability for chiller applications ...