Bile Acid

Bile Acid

Bile acids are steroid acids found predominantly in the bile of mammals. Bile salts are bile acids compounded with a cation, usually sodium. In humans, the salts of taurocholic acid and glycocholic acid (derivatives of cholic acid) represent approximately eighty percent of all bile salts. Bile acids, glycine and taurine conjugates, and 7-alpha-dehydroxylated derivatives (deoxycholic acid and lithocholic acid) are all found in human intestinal bile. An increase in bile flow is exhibited with an increased secretion of bile acids. The main function of bile acid is to facilitate the formation of micelles, which promotes processing of dietary fat.

Read more about Bile Acid:  Production and Distribution, Types, Regulation, Clinical Significance

Other articles related to "bile acid, acid, bile, bile acids, acids":

... Bile acid-CoAamino acid N-acyltransferase is an enzyme that in humans is encoded by the BAAT gene ... protein encoded by this gene is a liver enzyme that catalyzes the transfer of the bile acid moiety from the acyl-CoA thioester to either glycine or taurine, the second step in the ...
Se HCAT - Development
... SeHCAT is a taurine-conjugated bile acid analog which was synthesized for use as a radiopharmaceutical to investigate in vivo the enterohepatic ... shown to be absorbed from the gut and excreted into the bile at the same rate as cholic acid, one of the major natural bile acids in humans ... response to food, and is reabsorbed efficiently in the ileum, with kinetics similar to natural bile acids ...
... organelle Biological process • fatty acid beta-oxidation • bile acid biosynthetic process • bile acid metabolic process • androgen metabolic process • estrogen ... an enzyme involved in peroxisomal fatty acid beta-oxidation ... Peroxisomal beta-oxidation of fatty acids, originally described by Lazarow and de Duve (1976), is catalyzed by 3 enzymes acyl-CoA oxidase (see, e.g ...
Bile Acids - Types
... Bile salts constitute a large family of molecules, composed of a steroid structure with four rings, a five- or eight-carbon side-chain terminating in a carboxylic ... All bile acids have a hydroxyl group on position 3, which was derived from the parent molecule, cholesterol ... the initial step in the formation of a bile acid is the addition of a 7-alpha hydroxyl group ...
Bile Acid - Clinical Significance
... Since bile acids are made from endogenous cholesterol, the enterohepatic circulation of bile acids may be disrupted to lower cholesterol ... Bile acid sequestrants bind bile acids in the gut, preventing reabsorption ... In so doing, more endogenous cholesterol is shunted into the production of bile acids, thereby lowering cholesterol levels ...

Famous quotes containing the word bile:

    Mister Ward, don’t yur blud bile at the thawt that three million and a half of your culled brethren air a clanking their chains in the South?—Sez I, not a bile! Let ‘em clank!
    Artemus Ward (1834–1867)