AMY2B

Identifiers Symbols AMY2B; AMY2 External IDs OMIM: 104660 HomoloGene: 117989 ChEMBL: 2477 GeneCards: AMY2B Gene EC number 3.2.1.1

Gene Ontology
Molecular function	• alpha-amylase activity • metal ion binding
Cellular component	• extracellular region
Biological process	• carbohydrate metabolic process • digestion
Sources: Amigo / QuickGO

RNA expression pattern More reference expression data Orthologs Species Human Mouse Entrez 280 n/a Ensembl ENSG00000240038 n/a UniProt P19961 n/a RefSeq (mRNA) NM_020978 n/a RefSeq (protein) NP_066188 n/a Location (UCSC) Chr 1:
104.1 – 104.12 Mb n/a PubMed search n/a

Alpha-amylase 2B is an enzyme that in humans is encoded by the AMY2B gene.

Amylases are secreted proteins that hydrolyze 1,4-alpha-glucoside bonds in oligosaccharides and polysaccharides, and thus catalyze the first step in digestion of dietary starch and glycogen. The human genome has a cluster of several amylase genes that are expressed at high levels in either salivary gland or pancreas. This gene encodes an amylase isoenzyme produced by the pancreas.