Advanced Cell Technology, Incorporated (OTCBB: ACTC), is a biotechnology company located in Marlborough, Massachusetts, USA. The company specializes in the development and commercialization of cell therapies for the treatment of a variety of diseases. ACT is primarily developing stem cell-based technologies, both adult and human embryonic, and other methods and treatments in the area of regenerative medicine.
Formed in 1994, the company was led from 2005 to late 2010 by William M. Caldwell IV, Chairman and Chief Executive Officer. Upon Mr. Caldwell's death on December 13, 2010, Gary Rabin, a member of ACT's board of directors with experience in investment and capital raising, took over as Chairman and CEO.
ACT's Chief Scientific Officer is Robert Lanza, MD, who is also Adjunct Professor at Wake Forest University School of Medicine.
On August 23, 2006, the online edition of the science journal Nature published a paper by Dr. Lanza and others stating that his team had found a way to extract embryonic stem cells without destroying the actual embryo, deriving a stem cell line using a process similar to preimplantation genetic diagnosis, in which a single blastomere is extracted from a blastocyst. This technical achievement would potentially enable scientists to work with new lines of embryonic stem cells derived using public funding.
On November 22, 2010, the company announced that it had received approval from the U.S. Food and Drug Administration (FDA) to initiate the first-ever human clinical trial using embryonic stem cells to treat retinal disease
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