What is subthalamic nucleus?

  • (noun): An oval mass of gray matter located in the caudal part of the subthalamus; associated with the striate body.

Subthalamic Nucleus

The subthalamic nucleus is a small lens-shaped nucleus in the brain where it is, from a functional point of view, part of the basal ganglia system. In terms of anatomy, it is the major part of subthalamus. As suggested by its name, the subthalamic nucleus is located ventral to the thalamus. It is also dorsal to the substantia nigra and medial to the internal capsule. It was first described by Jules Bernard Luys in 1865, and the term corpus Luysi or Luys' body is still sometimes used.

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Some articles on subthalamic nucleus:

Ablative Brain Surgery - Uses - Parkinson's Disease
... potential target for treating a tremor in some countries, so is the subthalamic nucleus, although not in the United States due to its severe side ... for patients for whom DBS is not feasible, ablation of the subthalamic nucleus has been shown to be safe and effective ... In the case of such circumstances, a permanent lesion in the subthalamic nucleus (STN) is created as it is a more favourable surgical procedure ...
Primate Basal Ganglia System - Regulators of The Basal Ganglia Core - Subthalamic Nucleus, or Corpus Lyuisi - Subthalamo-lateropallidal Pacemaker
... It is particularly linked to the subthalamic nucleus by two-way connections ... neither the lateral pallidum or the subthalmic nucleus send axons to the thalamus ... The subthalamic nucleus and lateral pallidum are both fast-firing pacemakers ...
Overactive - Pathophysiology
... movements can be traced to improper modulation of the basal ganglia by the subthalamic nucleus ... In many cases, the excitatory output of the subthalamic nucleus is reduced, leading to a reduced inhibitory outflow of the basal ganglia ... The GPe projects to the subthalamic nucleus (STN), which then projects back to the GPi and GPe via excitatory, glutaminergic pathways ...
Subthalamic Fasciculus
... The subthalamic fasciculus is a tract which connects the subthalamic nucleus and the globus pallidus ... It is a bidirectional connection between the GP and the subthalamic nucleus, including (1) fibers running from the GPe to the subthalamic nucleus, and (2) fibers running from ...

Famous quotes containing the word nucleus:

    I could not undertake to form a nucleus of an institution for the development of infant minds, where none already existed. It would be too cruel.
    Henry David Thoreau (1817–1862)