What is spina bifida?

  • (noun): A not uncommon congenital defect in which a vertebra is malformed; unless several vertebrae are affected or there is myelomeningocele there are few symptoms; can be diagnosed by amniocentesis.
    Synonyms: rachischisis, schistorrhachis

Spina Bifida

Spina bifida (Latin: "split spine") is a developmental congenital disorder caused by the incomplete closing of the embryonic neural tube. Some vertebrae overlying the spinal cord are not fully formed and remain unfused and open. If the opening is large enough, this allows a portion of the spinal cord to protrude through the opening in the bones. There may or may not be a fluid-filled sac surrounding the spinal cord. Other neural tube defects include anencephaly, a condition in which the portion of the neural tube that will become the cerebrum does not close, and encephalocele, which results when other parts of the brain remain unfused.

Read more about Spina Bifida.

Some articles on spina bifida:

MOMS Study
... Spina bifida (Latin "split spine") is a developmental congenital disorder caused by the incomplete closing of the embryonic neural tube ... Spina bifida malformations fall into three categories spina bifida occulta, spina bifida cystica with meningocele, and spina bifida cystica with myelomeningocele ... The terms spina bifida and myelomeningocele are usually used interchangeably ...
MOMS Study - Fetal Surgery Research - Endoscopic Fetal Surgery
... superior visualization of fetoscopic spina bifida closure, is called PACI (partial amniotic fluid insufflation), and has been safe for mothers and fetuses alike in over 70 ... approach do not occur following minimally-invasive fetoscopic closure of spina bifida aperta ... Moreover, following the fetoscopic approach, postnatal spina bifida surgery can now be avoided in most patients ...
MOMS Trial - Outcomes of The Trial
... The trial demonstrated that outcomes after prenatal spina bifida treatment are improved to the degree that the benefits of the surgery outweigh the maternal risks ... the study found that Babies that underwent fetal repair of spina bifida were half as likely to need a ventricular shunt ... Based on these outcomes, fetal repair of spina bifida is now considered a standard of care at some fetal centers ...
Spina Bifida - Notable People
... Notable people with spina bifida include Tanni Grey-Thompson - Welsh Paralympic athlete, member of British House of Lords Blaine Harrison - lead singer ...
MOMS Trial - History
... Joseph Bruner, attempted to close spina bifida in 4 human fetuses using a skin graft from the mother using specialized telescope called a laparoscope ... Adzick and team at The Children’s Hospital of Philadelphia performed open fetal surgery for spina bifida in an early gestation fetus (22 week gestation fetus) with a successful outcome. 4 medical centers conducted 253 open spina bifida repairs prior to the MOMs trial ...